Volume 4(1); Jan-Feb 2013

Commentaries

Human Coronavirus EMC Is Not the Same as Severe Acute Respiratory Syndrome Coronavirus

Stanley Perlman, Jincun Zhao

mBio. 2013 Jan-Feb; 4(1): e00002-13. Published online 2013 Jan 15. doi: 10.1128/mBio.00002-13

PMCID:: PMC3551544

Article PDF–92K

Carbon Catabolite Control in Candida albicans: New Wrinkles in Metabolism

Michael C. Lorenz

mBio. 2013 Jan-Feb; 4(1): e00034-13. Published online 2013 Feb 5. doi: 10.1128/mBio.00034-13

PMCID:: PMC3624514

Article PDF–115K

Honeybees and Tetracycline Resistance

Stuart B. Levy, Bonnie M. Marshall

mBio. 2013 Jan-Feb; 4(1): e00045-13. Published online 2013 Feb 12. doi: 10.1128/mBio.00045-13

PMCID:: PMC3573660

Article PDF–91K

Bloody coli: a Gene Cocktail in Escherichia coli O104:H4

Fernando Baquero, Raquel Tobes

mBio. 2013 Jan-Feb; 4(1): e00066-13. Published online 2013 Feb 19. doi: 10.1128/mBio.00066-13

PMCID:: PMC3624515

Article PDF–188K

The New Age of Virus Discovery: Genomic Analysis of a Novel Human Betacoronavirus Isolated from a Fatal Case of Pneumonia

Kathryn V. Holmes, Samuel R. Dominguez

mBio. 2013 Jan-Feb; 4(1): e00548-12. Published online 2013 Jan 8. doi: 10.1128/mBio.00548-12

PMCID:: PMC3546555

Article PDF–101K

Observation

Cultivation of an Obligate Fe(II)-Oxidizing Lithoautotrophic Bacterium Using Electrodes

Zarath M. Summers, Jeffrey A. Gralnick, Daniel R. Bond

mBio. 2013 Jan-Feb; 4(1): e00420-12. Published online 2013 Jan 29. doi: 10.1128/mBio.00420-12

PMCID:: PMC3560526

Article PDF–560K

De Novo Assembly of the Pneumocystis jirovecii Genome from a Single Bronchoalveolar Lavage Fluid Specimen from a Patient

Ousmane H. Cissé, Marco Pagni, Philippe M. Hauser

mBio. 2013 Jan-Feb; 4(1): e00428-12. Published online 2012 Dec 26. doi: 10.1128/mBio.00428-12

PMCID:: PMC3531804

Article PDF–461K

Candida albicans Morphogenesis Is Not Required for Macrophage Interleukin 1β Production

Melanie Wellington, Kristy Koselny, Damian J. Krysan

mBio. 2013 Jan-Feb; 4(1): e00433-12. Published online 2012 Dec 26. doi: 10.1128/mBio.00433-12

PMCID:: PMC3531805

Article PDF–1.0M

Flavin Electron Shuttles Dominate Extracellular Electron Transfer by Shewanella oneidensis

Nicholas J. Kotloski, Jeffrey A. Gralnick

mBio. 2013 Jan-Feb; 4(1): e00553-12. Published online 2013 Jan 15. doi: 10.1128/mBio.00553-12

PMCID:: PMC3551548

Article PDF–583K

Efficient Replication of the Novel Human Betacoronavirus EMC on Primary Human Epithelium Highlights Its Zoonotic Potential

Eveline Kindler, Hulda R. Jónsdóttir, Doreen Muth, Ole J. Hamming, Rune Hartmann, Regulo Rodriguez, Robert Geffers, Ron A. M. Fouchier, Christian Drosten, Marcel A. Müller, Ronald Dijkman, Volker Thiel

mBio. 2013 Jan-Feb; 4(1): e00611-12. Published online 2013 Feb 19. doi: 10.1128/mBio.00611-12

PMCID:: PMC3573664

Article PDF–2.7M

Males Are Overrepresented among Life Science Researchers Committing Scientific Misconduct

Ferric C. Fang, Joan W. Bennett, Arturo Casadevall

mBio. 2013 Jan-Feb; 4(1): e00640-12. Published online 2013 Jan 22. doi: 10.1128/mBio.00640-12

PMCID:: PMC3551552

Article PDF–562K

Research Articles

Structural and Functional Analysis of the Pore-Forming Toxin NetB from Clostridium perfringens

Xu-Xia Yan, Corrine J. Porter, Simon P. Hardy, David Steer, A. Ian Smith, Noelene S. Quinsey, Victoria Hughes, Jackie K. Cheung, Anthony L. Keyburn, Magne Kaldhusdal, Robert J. Moore, Trudi L. Bannam, James C. Whisstock, Julian I. Rood

mBio. 2013 Jan-Feb; 4(1): e00019-13. Published online 2013 Feb 5. doi: 10.1128/mBio.00019-13

PMCID:: PMC3565830

Article PDF–1.9M

RpoS Contributes to Phagocyte Oxidase-Mediated Stress Resistance during Urinary Tract Infection by Escherichia coli CFT073

Andrew J. Hryckowian, Rodney A. Welch

mBio. 2013 Jan-Feb; 4(1): e00023-13. Published online 2013 Feb 12. doi: 10.1128/mBio.00023-13

PMCID:: PMC3573659

Article PDF–634K

RidA Proteins Prevent Metabolic Damage Inflicted by PLP-Dependent Dehydratases in All Domains of Life

Jennifer A. Lambrecht, George E. Schmitz, Diana M. Downs

mBio. 2013 Jan-Feb; 4(1): e00033-13. Published online 2013 Feb 5. doi: 10.1128/mBio.00033-13

PMCID:: PMC3565831

Article PDF–607K

A Quorum-Sensing-Induced Bacteriophage Defense Mechanism

Nina Molin Høyland-Kroghsbo, Rasmus Baadsgaard Mærkedahl, Sine Lo Svenningsen

mBio. 2013 Jan-Feb; 4(1): e00362-12. Published online 2013 Feb 19. doi: 10.1128/mBio.00362-12

PMCID:: PMC3624510

Article PDF–1.0M

Microbial Composition of Human Appendices from Patients following Appendectomy

Caitriona M. Guinane, Amany Tadrous, Fiona Fouhy, C. Anthony Ryan, Eugene M. Dempsey, Brendan Murphy, Emmet Andrews, Paul D. Cotter, Catherine Stanton, R. Paul Ross

mBio. 2013 Jan-Feb; 4(1): e00366-12. Published online 2013 Jan 15. doi: 10.1128/mBio.00366-12

PMCID:: PMC3551545

Article PDF–617K

Targeted Amino Acid Substitutions Impair Streptolysin O Toxicity and Group A Streptococcus Virulence

Emiliano Chiarot, Cristina Faralla, Nico Chiappini, Giovanna Tuscano, Fabiana Falugi, Gabriella Gambellini, Annarita Taddei, Sabrina Capo, Elena Cartocci, Daniele Veggi, Alessia Corrado, Simona Mangiavacchi, Simona Tavarini, Maria Scarselli, Robert Janulczyk, Guido Grandi, Immaculada Margarit, Giuliano Bensi

mBio. 2013 Jan-Feb; 4(1): e00387-12. Published online 2013 Jan 8. doi: 10.1128/mBio.00387-12

PMCID:: PMC3546560

Article PDF–1.2M

The Rnf Complex of Clostridium ljungdahlii Is a Proton-Translocating Ferredoxin:NAD⁺ Oxidoreductase Essential for Autotrophic Growth

Pier-Luc Tremblay, Tian Zhang, Shabir A. Dar, Ching Leang, Derek R. Lovley

mBio. 2013 Jan-Feb; 4(1): e00406-12. Published online 2012 Dec 26. doi: 10.1128/mBio.00406-12

PMCID:: PMC3531802

Article PDF–1.3M

Entry and Killing of Tetrahymena thermophila by Bacterially Produced Shiga Toxin

Gino Stolfa, Gerald B. Koudelka

mBio. 2013 Jan-Feb; 4(1): e00416-12. Published online 2012 Dec 26. doi: 10.1128/mBio.00416-12

PMCID:: PMC3531803

Article PDF–922K

Sensing of Bacterial Type IV Secretion via the Unfolded Protein Response

Maarten F. de Jong, Tregei Starr, Maria G. Winter, Andreas B. den Hartigh, Robert Child, Leigh A. Knodler, Jan Maarten van Dijl, Jean Celli, Renée M. Tsolis

mBio. 2013 Jan-Feb; 4(1): e00418-12. Published online 2013 Feb 19. doi: 10.1128/mBio.00418-12

PMCID:: PMC3624511

Article PDF–1.9M

Broad Conditions Favor the Evolution of Phase-Variable Loci

M. E. Palmer, M. Lipsitch, E. R. Moxon, C. D. Bayliss

mBio. 2013 Jan-Feb; 4(1): e00430-12. Published online 2013 Jan 8. doi: 10.1128/mBio.00430-12

PMCID:: PMC3546556

Article PDF–2.3M

Comparative Genomics of Recent Shiga Toxin-Producing Escherichia coli O104:H4: Short-Term Evolution of an Emerging Pathogen

Yonatan H. Grad, Paul Godfrey, Gustavo C. Cerquiera, Patricia Mariani-Kurkdjian, Malika Gouali, Edouard Bingen, Terrence P. Shea, Brian J. Haas, Allison Griggs, Sarah Young, Qiandong Zeng, Marc Lipsitch, Matthew K. Waldor, François-Xavier Weill, Jennifer R. Wortman, William P. Hanage

mBio. 2013 Jan-Feb; 4(1): e00452-12. Published online 2013 Jan 22. doi: 10.1128/mBio.00452-12

PMCID:: PMC3551546

Article PDF–1.8M

Biochemical and Structural Evidence in Support of a Coherent Model for the Formation of the Double-Helical Influenza A Virus Ribonucleoprotein

Qiaozhen Ye, Tom S. Y. Guu, Douglas A. Mata, Rei-Lin Kuo, Bartram Smith, Robert M. Krug, Yizhi J. Tao

mBio. 2013 Jan-Feb; 4(1): e00467-12. Published online 2012 Dec 26. doi: 10.1128/mBio.00467-12

PMCID:: PMC3531806

Article PDF–2.1M

Critical Roles for Lipomannan and Lipoarabinomannan in Cell Wall Integrity of Mycobacteria and Pathogenesis of Tuberculosis

Takeshi Fukuda, Takayuki Matsumura, Manabu Ato, Maho Hamasaki, Yukiko Nishiuchi, Yoshiko Murakami, Yusuke Maeda, Tamotsu Yoshimori, Sohkichi Matsumoto, Kazuo Kobayashi, Taroh Kinoshita, Yasu S. Morita

mBio. 2013 Jan-Feb; 4(1): e00472-12. Published online 2013 Feb 19. doi: 10.1128/mBio.00472-12

PMCID:: PMC3573661

Article PDF–2.4M

Cryptococcus neoformans Rim101 Is Associated with Cell Wall Remodeling and Evasion of the Host Immune Responses

Teresa R. O'Meara, Stephanie M. Holmer, Kyla Selvig, Fred Dietrich, J. Andrew Alspaugh

mBio. 2013 Jan-Feb; 4(1): e00522-12. Published online 2013 Jan 15. doi: 10.1128/mBio.00522-12

PMCID:: PMC3551547

Article PDF–3.1M

Quantifying Pathogen Surveillance Using Temporal Genomic Data

Joseph M. Chan, Raul Rabadan

mBio. 2013 Jan-Feb; 4(1): e00524-12. Published online 2013 Jan 29. doi: 10.1128/mBio.00524-12

PMCID:: PMC3560527

Article PDF–719K

Control of Candida albicans Metabolism and Biofilm Formation by Pseudomonas aeruginosa Phenazines

Diana K. Morales, Nora Grahl, Chinweike Okegbe, Lars E. P. Dietrich, Nicholas J. Jacobs, Deborah A. Hogan

mBio. 2013 Jan-Feb; 4(1): e00526-12. Published online 2013 Jan 29. doi: 10.1128/mBio.00526-12

PMCID:: PMC3560528

Article PDF–1.4M

Pilus Adhesin RrgA Interacts with Complement Receptor 3, Thereby Affecting Macrophage Function and Systemic Pneumococcal Disease

Sofia Orrskog, Samuli Rounioja, Tiziana Spadafina, Marilena Gallotta, Martin Norman, Karina Hentrich, Stefan Fälker, Sofia Ygberg-Eriksson, Mike Hasenberg, Björn Johansson, Liisa M. Uotila, Carl G. Gahmberg, Michèle Barocchi, Matthias Gunzer, Staffan Normark, Birgitta Henriques-Normark

mBio. 2013 Jan-Feb; 4(1): e00535-12. Published online 2012 Dec 26. doi: 10.1128/mBio.00535-12

PMCID:: PMC3531807

Article PDF–2.1M

A Genetic Resource for Rapid and Comprehensive Phenotype Screening of Nonessential Staphylococcus aureus Genes

Paul D. Fey, Jennifer L. Endres, Vijaya Kumar Yajjala, Todd J. Widhelm, Robert J. Boissy, Jeffrey L. Bose, Kenneth W. Bayles

mBio. 2013 Jan-Feb; 4(1): e00537-12. Published online 2013 Feb 12. doi: 10.1128/mBio.00537-12

PMCID:: PMC3573662

Article PDF–3.3M

Characterization of a Diffusible Signaling Factor from Xylella fastidiosa

Ellen D. Beaulieu, Michael Ionescu, Subhadeep Chatterjee, Kenji Yokota, Dirk Trauner, Steven Lindow

mBio. 2013 Jan-Feb; 4(1): e00539-12. Published online 2013 Jan 8. doi: 10.1128/mBio.00539-12

PMCID:: PMC3546559

Article PDF–994K

Proteins Needed to Activate a Transcriptional Response to the Reactive Oxygen Species Singlet Oxygen

Tae-Wook Nam, Eva C. Ziegelhoffer, Rachelle A. S. Lemke, Timothy J. Donohue

mBio. 2013 Jan-Feb; 4(1): e00541-12. Published online 2013 Jan 8. doi: 10.1128/mBio.00541-12

PMCID:: PMC3546557

Article PDF–1.2M

Next-Generation Sequencing of Small RNAs from HIV-Infected Cells Identifies Phased microRNA Expression Patterns and Candidate Novel microRNAs Differentially Expressed upon Infection

Stewart T. Chang, Matthew J. Thomas, Pavel Sova, Richard R. Green, Robert E. Palermo, Michael G. Katze

mBio. 2013 Jan-Feb; 4(1): e00549-12. Published online 2013 Feb 5. doi: 10.1128/mBio.00549-12

PMCID:: PMC3560529

Article PDF–595K

Salmonella enterica Suppresses Pectobacterium carotovorum subsp. carotovorum Population and Soft Rot Progression by Acidifying the Microaerophilic Environment

Grace Kwan, Amy O. Charkowski, Jeri D. Barak

mBio. 2013 Jan-Feb; 4(1): e00557-12. Published online 2013 Feb 12. doi: 10.1128/mBio.00557-12

PMCID:: PMC3573663

Article PDF–1.0M

A Novel Selective LSD1/KDM1A Inhibitor Epigenetically Blocks Herpes Simplex Virus Lytic Replication and Reactivation from Latency

Yu Liang, Debra Quenelle, Jodi L. Vogel, Cristina Mascaro, Alberto Ortega, Thomas M. Kristie

mBio. 2013 Jan-Feb; 4(1): e00558-12. Published online 2013 Feb 5. doi: 10.1128/mBio.00558-12

PMCID:: PMC3565832

Article PDF–2.3M

Modulation of Epstein-Barr Virus Glycoprotein B (gB) Fusion Activity by the gB Cytoplasmic Tail Domain

Nicholas J. Garcia, Jia Chen, Richard Longnecker

mBio. 2013 Jan-Feb; 4(1): e00571-12. Published online 2013 Jan 22. doi: 10.1128/mBio.00571-12

PMCID:: PMC3551549

Article PDF–1.9M

Genomic Insights into the Atopic Eczema-Associated Skin Commensal Yeast Malassezia sympodialis

Anastasia Gioti, Björn Nystedt, Wenjun Li, Jun Xu, Anna Andersson, Anna F. Averette, Karin Münch, Xuying Wang, Catharine Kappauf, Joanne M. Kingsbury, Bart Kraak, Louise A. Walker, Henrik J. Johansson, Tina Holm, Janne Lehtiö, Jason E. Stajich, Piotr Mieczkowski, Regine Kahmann, John C. Kennell, Maria E. Cardenas, Joakim Lundeberg, Charles W. Saunders, Teun Boekhout, Thomas L. Dawson, Carol A. Munro, Piet W. J. de Groot, Geraldine Butler, Joseph Heitman, Annika Scheynius

mBio. 2013 Jan-Feb; 4(1): e00572-12. Published online 2013 Jan 22. doi: 10.1128/mBio.00572-12

PMCID:: PMC3560662

Article PDF–2.6M

Kinetics of Facultative Heterochromatin and Polycomb Group Protein Association with the Herpes Simplex Viral Genome during Establishment of Latent Infection

Anna R. Cliffe, Donald M. Coen, David M. Knipe

mBio. 2013 Jan-Feb; 4(1): e00590-12. Published online 2013 Jan 15. doi: 10.1128/mBio.00590-12

PMCID:: PMC3551550

Article PDF–868K

Human Claudin-8 and -14 Are Receptors Capable of Conveying the Cytotoxic Effects of Clostridium perfringens Enterotoxin

Archana Shrestha, Bruce A. McClane

mBio. 2013 Jan-Feb; 4(1): e00594-12. Published online 2013 Jan 15. doi: 10.1128/mBio.00594-12

PMCID:: PMC3551551

Article PDF–1.8M

NEAT1 Long Noncoding RNA and Paraspeckle Bodies Modulate HIV-1 Posttranscriptional Expression

Quan Zhang, Chia-Yen Chen, Venkat S. R. K. Yedavalli, Kuan-Teh Jeang

mBio. 2013 Jan-Feb; 4(1): e00596-12. Published online 2013 Jan 29. doi: 10.1128/mBio.00596-12

PMCID:: PMC3560530

Article PDF–2.2M

Dectin-1 Is Required for Resistance to Coccidioidomycosis in Mice

Suganya Viriyakosol, Maria del Pilar Jimenez, Michael A. Gurney, Mark E. Ashbaugh, Joshua Fierer

mBio. 2013 Jan-Feb; 4(1): e00597-12. Published online 2013 Feb 5. doi: 10.1128/mBio.00597-12

PMCID:: PMC3562125

Article PDF–1.5M

Host Pathways Important for Coxiella burnetii Infection Revealed by Genome-Wide RNA Interference Screening

Justin A. McDonough, Hayley J. Newton, Scott Klum, Rachel Swiss, Hervé Agaisse, Craig R. Roy

mBio. 2013 Jan-Feb; 4(1): e00606-12. Published online 2013 Jan 29. doi: 10.1128/mBio.00606-12

PMCID:: PMC3560531

Article PDF–2.8M

Evidence for an ABC-Type Riboflavin Transporter System in Pathogenic Spirochetes

Ranjit K. Deka, Chad A. Brautigam, Brent A. Biddy, Wei Z. Liu, Michael V. Norgard

mBio. 2013 Jan-Feb; 4(1): e00615-12. Published online 2013 Feb 12. doi: 10.1128/mBio.00615-12

PMCID:: PMC3573665

Article PDF–2.0M

Inflammasome Components Coordinate Autophagy and Pyroptosis as Macrophage Responses to Infection

Brenda G. Byrne, Jean-Francois Dubuisson, Amrita D. Joshi, Jenny J. Persson, Michele S. Swanson

mBio. 2013 Jan-Feb; 4(1): e00620-12. Published online 2013 Feb 12. doi: 10.1128/mBio.00620-12

PMCID:: PMC3573666

Article PDF–2.3M

A Decade of Plague in Mahajanga, Madagascar: Insights into the Global Maritime Spread of Pandemic Plague

Amy J. Vogler, Fabien Chan, Roxanne Nottingham, Genevieve Andersen, Kevin Drees, Stephen M. Beckstrom-Sternberg, David M. Wagner, Suzanne Chanteau, Paul Keim

mBio. 2013 Jan-Feb; 4(1): e00623-12. Published online 2013 Feb 12. doi: 10.1128/mBio.00623-12

PMCID:: PMC3573667

Article PDF–917K

Five New Genes Are Important for Common Polysaccharide Antigen Biosynthesis in Pseudomonas aeruginosa

Youai Hao, Jerry D. King, Steven Huszczynski, Dana Kocíncová, Joseph S. Lam

mBio. 2013 Jan-Feb; 4(1): e00631-12. Published online 2013 Jan 22. doi: 10.1128/mBio.00631-12

PMCID:: PMC3560663

Article PDF–1.6M

Kdo Hydrolase Is Required for Francisella tularensis Virulence and Evasion of TLR2-Mediated Innate Immunity

Nihal A. Okan, Sabina Chalabaev, Tae-Hyun Kim, Avner Fink, Robin A. Ross, Dennis L. Kasper

mBio. 2013 Jan-Feb; 4(1): e00638-12. Published online 2013 Feb 12. doi: 10.1128/mBio.00638-12

PMCID:: PMC3573668

Article PDF–1.8M

Errata

Contrasting Life Strategies of Viruses That Infect Photo- and Heterotrophic Bacteria, as Revealed by Viral Tagging

Li Deng, Ann Gregory, Suzan Yilmaz, Bonnie T. Poulos, Philip Hugenholtz, Matthew B. Sullivan

mBio. 2013 Jan-Feb; 4(1): e00516-12. Published online 2013 Jan 8. doi: 10.1128/mBio.00516-12

Corrects:: mBio. 2012 Nov-Dec; 3(6): e00373-12.

PMCID:: PMC3542626

Correction PDF–543K

Staphylococcus aureus CC398: Host Adaptation and Emergence of Methicillin Resistance in Livestock

Lance B. Price, Marc Stegger, Henrik Hasman, Maliha Aziz, Jesper Larsen, Paal Skytt Andersen, Talima Pearson, Andrew E. Waters, Jeffrey T. Foster, James Schupp, John Gillece, Elizabeth Driebe, Cindy M. Liu, Burkhard Springer, Irena Zdovc, Antonio Battisti, Alessia Franco, Jacek Żmudzki, Stefan Schwarz, Patrick Butaye, Eric Jouy, Constanca Pomba, M. Concepción Porrero, Raymond Ruimy, Tara C. Smith, D. Ashley Robinson, J. Scott Weese, Carmen Sofia Arriola, Fangyou Yu, Frederic Laurent, Paul Keim, Robert Skov, Frank M. Aarestrup

mBio. 2013 Jan-Feb; 4(1): e00520-12. Published online 2013 Jan 8. doi: 10.1128/mBio.00520-12

Corrects:: mBio. 2012 Jan-Feb; 3(1): e00305-11.

PMCID:: PMC3546554

Correction PDF–59K

Galactose Metabolism Plays a Crucial Role in Biofilm Formation by Bacillus subtilis

Yunrong Chai, Pascale B. Beauregard, Hera Vlamakis, Richard Losick, Roberto Kolter

mBio. 2013 Jan-Feb; 4(1): e00555-12. Published online 2013 Jan 8. doi: 10.1128/mBio.00555-12

Corrects:: mBio. 2012 Jul-Aug; 3(4): e00184-12.

PMCID:: PMC3546558

Correction PDF–317K

Articles from mBio are provided here courtesy of American Society for Microbiology (ASM)